Think all allergy pills make you sleepy? Loratadine usually doesn’t. It’s an over-the-counter antihistamine used for hay fever, itchy eyes, sneezing, runny nose, and hives. Many people pick loratadine because it works for about 24 hours and lets you get through the day without grogginess.
How it works: loratadine blocks histamine, the chemical your body releases during an allergic reaction. That stops the sneezing, itching, and watery eyes rather than masking symptoms with heavy sedation.
Adults and kids 6 years and older: 10 mg once a day (tablet or capsule). Kids 2–5 years: usually 5 mg syrup once a day — check the product label for exact dosing and use a proper measuring device. Do not give loratadine to children under 2 unless a doctor says so. If you miss a dose, take it as soon as you remember; don’t double up the next day.
Take loratadine with or without food. If you have liver or kidney problems, your doctor may suggest a lower dose. Always read the package directions and talk to your pharmacist if you’re unsure.
Onset is usually within 1–3 hours and relief lasts about 24 hours. Common side effects are mild: headache, dry mouth, and rarely a little drowsiness. Serious reactions are uncommon, but stop the drug and seek help if you develop swelling of the face, lips, throat, or trouble breathing — these can be signs of a severe allergic reaction.
Drug interactions to watch for: some antifungals (like ketoconazole), certain antibiotics (like erythromycin), and ritonavir can raise loratadine levels. Mixing with alcohol or sedatives can increase drowsiness in some people, so be cautious until you know how loratadine affects you. If you take other prescription meds, ask your doctor or pharmacist about interactions.
Pregnant or breastfeeding? Talk to your healthcare provider before taking loratadine. They can weigh the benefits and risks and suggest safer options if needed.
Using loratadine for hives? It often helps reduce itch and rash. For chronic or severe hives, your doctor may recommend higher doses or a different treatment plan. For asthma symptoms or severe allergic reactions (anaphylaxis), loratadine is not a substitute for emergency care or an inhaler.
Want to compare options? Cetirizine can be slightly stronger but may cause more drowsiness. Fexofenadine is another non-drowsy choice that some people prefer. If one antihistamine doesn’t help, ask a clinician about switching or combining strategies.
Final practical tips: stick to the recommended dose, store medication away from heat and moisture, and check labels for combination products (some cold medicines include antihistamines plus decongestants). If symptoms persist or get worse after several days of OTC treatment, see your doctor for a proper plan.
Need more specific guidance? Our site has articles on allergy medicine comparisons, dosing guides, and where to buy safely online. Use those to find the right option for your situation.
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